Desire takes place in the research institute of the same name, located on a remote island. Aparently the researchs being conducted have some sort of unnoficial link with the military and so journalist Albert Macdgul is sent to investigate and see what he can find. At the same time Tina, a young girl, is washed ashore in the island with no recolection of what has happened to her or who she is, and meanwhile the technical manager at Desire Makoto Izumi seems to think something weird is going on with the researchs being conducted. You’ll play through 4 chapters which make up the same storyline, but viewed by different characters. In each chapter you’ll see the events and situations from different angles and uncover layers and layers of the main plotline which twists and bends in standard C’s Ware fashion (and in the way you’ll hook up with all of Desire’s female population!).